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Vitro Safe Systems Limited

The Problem

Fluctuations in environmental conditions during IVF (In Vitro Fertilisation) and stem cell procedures can compromise cell viability leading to reduced success rates in the generation of viable embryos and stem cell lines, respectively. IVF and stem cell procedures are traditionally conducted using open fronted laminar flow cabinets that offer poor control of environmental conditions such as temperature and pH. Compounding this, the open nature of the laminar flow cabinets can lead to contamination of the cells not only by the operator but by volatile organic compounds and microbes that can be of particular concern in sensitive procedures.

The Solution

The technology, which is being patented for The Newcastle Upon Tyne Hospitals NHS by NHS Innovations North, comprises a series of enclosed isolators linked together with integrated  incubators to provide the first totally enclosed IVF process from oocyte retrieval to embryo transfer. This is combined with a heated carbon dioxide enriched air supply and filtration using HEPA and activated carbon filters to maintain and control a stable environment. The stable environmental conditions that can be achieved throughout the IVF process through the use of the IVF Isolation Cabinet System reduces cellular stress and increases the viability of embryos.

Benefits to the NHS

Preliminary clinical data indicates that the IVF Isolation Cabinet System promotes increased embryo viability and significantly improves pregnancy rates. The IVF Isolation Cabinet System has been shown to increase clinical pregnancy rates. This has clear benefits both to patient care and the cost effectiveness of IVF treatment by the NHS. Moreover, staff and in particular trainee embryologists have benefited from the use of the IVF Isolation Cabinet System as the controlled environment in which micromanipulation takes place eases the time constraints which would otherwise be placed upon the staff. The IVF Isolation Cabinet System was launched under the brand name Vitro Safe Systems at the European Society of Human Reproduction and Embryology Annual Conference 2008 to exceptionally positive feedback.

For further information please contact Louise Shaw on 0191 5164400 or email Louise.Shaw@nhsinnovationsnorth.org.uk 

24/Feb/2010

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