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Harlequin ABC Medium

The Problem

Members of the genus Salmonella constitute the most significant cause of food poisoning in the UK with over 300,000 cases reported annually according to HPA estimates. At present, the only effective means of diagnosis involves cultural isolation of the organisms. This is not however a straightforward process as specialised media and reagents are required to isolate small numbers of Sallmonellae from a massive amount of commensal micro-flora.

The Solution

The product was developed by Dr’s Michael Ford and John Perry from The Newcastle Upon Tyne Hospitals NHS Foundation Trust, and differentiates Salmonellae from other members of the Enterobacteriaceae family based on their ability to produce alpha galactosidase. This activity  is visualised using a dual chromogen system that can be used with both food and clinical samples.

Benefits to the NHS

Isolation of Salmonella spp. by culture remains the most reliable method of detection. However, most media are non-specific and place a heavy burden on the central laboratory in terms of secondary biochemical and serological testing. With improved specificity, the Harlequin™ ABC medium dramatically reduces false positives, saving NHS Trusts time and money in terms of both labour and consumables. The Harlequin™ ABC medium has been successfully licensed to the microbiology company Lab M Limited (www.labm.com).

For further information please contact Nicola Wesley on 0191 5164400 or email nicola.wesley@nhsinnovationsnorth.org.uk

24/Feb/2010

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